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Case Reports
. 2014 Dec 13:12:382.
doi: 10.1186/1477-7819-12-382.

Three synchronous, sporadic and separate periampullary and pancreatic tumors: more than a coincidence?

Amit Sastry, Michael Wayne, Justin Steele, Mazen Iskandar, Songyang Yuan, Avram M Cooperman  1
Affiliations
Case Reports

Three synchronous, sporadic and separate periampullary and pancreatic tumors: more than a coincidence?

Amit Sastry et al. World J Surg Oncol. .

Abstract

Three sporadic, synchronous, and separate lesions in the ampulla of Vater and the head of the pancreas presented in an 81-year-old male. One was symptomatic and two were incidental. One was detected preoperatively (the ampullary lesion) and two by examination of the resected specimen (the neuroendocrine and pancreatic carcinomas). The case is summarized and the literature and the issue of commonality are reviewed.

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Figures

Figure 1
Figure 1
Adenosquamous carcinoma of the ampulla of Vater. (A) Gross image of tumor. (B) Solid nests with focal glandular formation. Hematoxylin and eosin stain, 400×.
Figure 2
Figure 2
Adenocarcinoma of uncinate process. (A) Gross image of tumor with periampullary tumor above it. (B) Tumor consists of variable sized and shaped invasive tumor glands in the background diffuse stoma fibrosis. Hematoxylin and eosin stain, 100×.
Figure 3
Figure 3
Neuroendocrine tumor of the anterior pancreas. Tumor shows the characteristic trabecular pattern and monotonous cells of endocrine neoplasm. Hematoxylin and eosin stain, 100×.
Figure 4
Figure 4
The relationship of the three tumors in the head of the pancreas. A, the adenosquamous ampullary cancer; B, the adenocarcinoma of the head of the pancreas; C, the neuroendocrine tumor.
See this image and copyright information in PMC

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