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Review
. 1989 May;21(1):25-37.
doi: 10.1016/0165-2427(89)90127-x.

FeLV-FAIDS-induced immunodeficiency syndrome in cats

J I Mullins  1 , E A Hoover, J Overbaugh, S L Quackenbush, P R Donahue, M L Poss
Affiliations
Review

FeLV-FAIDS-induced immunodeficiency syndrome in cats

J I Mullins et al. Vet Immunol Immunopathol. 1989 May.

Abstract

Findings are reviewed, relevant to elucidation of the pathogenic, genetic and biochemical properties of a single, genetically heterogeneous isolate of feline leukemia virus (FeLV-FAIDS) shown to induce fatal immunodeficiency disease in nearly 100% of inoculated cats. Hypotheses are suggested which pertain to the mechanism of T-cell killing by this virus, and which extrapolate findings in the FeLV-FAIDS animal model to AIDS induced in humans by human immunodeficiency virus (HIV).

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