Evaluation of pooled ocular and vaginal swabs by the Cepheid GeneXpert CT/NG assay for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae compared to the GenProbe Aptima Combo 2 Assay
- PMID: 25497459
- PMCID: PMC4383745
- DOI: 10.1016/j.diagmicrobio.2014.11.010
Evaluation of pooled ocular and vaginal swabs by the Cepheid GeneXpert CT/NG assay for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae compared to the GenProbe Aptima Combo 2 Assay
Abstract
Ocular swabs from Tanzania were tested for Chlamydia trachomatis (CT), and self-collected vaginal swabs collected through a home collection program, iwantthekit.org, were tested for Neisseria gonorrhoeae and CT to evaluate Cepheid GeneXpert for the use of pooling multiple specimens before testing. GeneXpert shows to be a promising test for pooling.
Keywords: Chlamydia trachomatis; Neisseria gonorrhoeae; Pooling; Trachoma.
Copyright © 2015 Elsevier Inc. All rights reserved.
Conflict of interest statement
C. Gaydos discloses potential conflict of interest as she has been the recipient of research grants from or been a speaker for Cepheid and Gen-Probe/Hologic.
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