Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 May;138(Pt 5):e349.
doi: 10.1093/brain/awu341. Epub 2014 Dec 13.

Parkinsonism in GTP cyclohydrolase 1 mutation carriers

Ilaria Guella  1 , Holly E Sherman  2 , Silke Appel-Cresswell  3 , Alex Rajput  4 , Ali H Rajput  4 , Matthew J Farrer  2
Affiliations
Comment

Parkinsonism in GTP cyclohydrolase 1 mutation carriers

Ilaria Guella et al. Brain. 2015 May.
No abstract available

PubMed Disclaimer

Comment in

Comment on

  • Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
    Mencacci NE, Isaias IU, Reich MM, Ganos C, Plagnol V, Polke JM, Bras J, Hersheson J, Stamelou M, Pittman AM, Noyce AJ, Mok KY, Opladen T, Kunstmann E, Hodecker S, Münchau A, Volkmann J, Samnick S, Sidle K, Nanji T, Sweeney MG, Houlden H, Batla A, Zecchinelli AL, Pezzoli G, Marotta G, Lees A, Alegria P, Krack P, Cormier-Dequaire F, Lesage S, Brice A, Heutink P, Gasser T, Lubbe SJ, Morris HR, Taba P, Koks S, Majounie E, Raphael Gibbs J, Singleton A, Hardy J, Klebe S, Bhatia KP, Wood NW; International Parkinson’s Disease Genomics Consortium and UCL-exomes consortium. Mencacci NE, et al. Brain. 2014 Sep;137(Pt 9):2480-92. doi: 10.1093/brain/awu179. Epub 2014 Jul 2. Brain. 2014. PMID: 24993959 Free PMC article.

References

    1. Cobb SA, Wider C, Ross OA, Mata IF, Adler CH, Rajput A, et al. GCH1 in early-onset Parkinson's disease. Mov Disord. 2009;24:2070–5. - PubMed
    1. Eggers C, Volk AE, Kahraman D, Fink GR, Leube B, Schmidt M, et al. Are dopa-responsive dystonia and Parkinson's disease related disorders? A case report. Parkinsonism Relat Disord. 2012;18:666–8. - PubMed
    1. Furukawa Y, Lang AE, Trugman JM, Bird TD, Hunter A, Sadeh M, et al. Gender-related penetrance and de novo GTP-cyclohydrolase I gene mutations in dopa-responsive dystonia. Neurology. 1998;50:1015–20. - PubMed
    1. Hertz JM, Ostergaard K, Juncker I, Pedersen S, Romstad A, Moller LB, et al. Low frequency of Parkin, tyrosine hydroxylase, and GTP cyclohydrolase I gene mutations in a Danish population of early-onset Parkinson's Disease. Eur J Neurol. 2006;13:385–90. - PubMed
    1. Hjermind LE, Johannsen LG, Blau N, Wevers RA, Lucking CB, Hertz JM, et al. Dopa-responsive dystonia and early-onset Parkinson's disease in a patient with GTP cyclohydrolase I deficiency? Mov Disord. 2006;21:679–82. - PubMed

Substances