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Review
. 1989 May;56(1):51-61.
doi: 10.1007/BF00822584.

Physiological significance and bioenergetic aspects of glucose dehydrogenase

O M Neijssel  1 , R W Hommes, P W Postma, D W Tempest
Affiliations
Review

Physiological significance and bioenergetic aspects of glucose dehydrogenase

O M Neijssel et al. Antonie Van Leeuwenhoek. 1989 May.

Abstract

The regulation of the PQQ-linked glucose dehydrogenase in different organisms is reviewed. It is concluded that this enzyme functions as an auxiliary energy-generating mechanism, because it is maximally synthesized under conditions of energy stress. It is now definitively established that the oxidation of glucose to gluconate generates metabolically useful energy. The magnitude of the contribution of the oxidation of glucose to gluconate via this enzyme to the growth yield of organisms such as Acinetobacter calcoaceticus is not yet clear.

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