Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1989 Jul;8(7):651-3.
doi: 10.1007/BF01968150.

Comparative antimicrobial activity of the new macrolides against Borrelia burgdorferi

V Preac-Mursic  1 , B Wilske, G Schierz, E Süss, B Gross
Affiliations
Comparative Study

Comparative antimicrobial activity of the new macrolides against Borrelia burgdorferi

V Preac-Mursic et al. Eur J Clin Microbiol Infect Dis. 1989 Jul.

Abstract

The in vitro and in vivo activity of the new macrolides azithromycin, clarithromycin and roxythromycin was compared with that of erythromycin against Borrelia burgdorferi. In in vitro tests using ten clinical isolates all macrolides were highly active against Borrelia burgdorferi (MIC90 0.015-0.06 micrograms/ml). Azithromycin was more potent than the other macrolides in experimental animal infection, eradicating the organism in all animals tested at a dosage of 8 mg/kg.

PubMed Disclaimer

References

    1. Infection. 1984 Sep-Oct;12(5):331-7 - PubMed
    1. Antimicrob Agents Chemother. 1987 Feb;31(2):164-7 - PubMed
    1. Ann Intern Med. 1981 Jan;94(1):137 - PubMed
    1. Ann Intern Med. 1983 Dec;99(6):767-72 - PubMed
    1. Antimicrob Agents Chemother. 1988 Nov;32(11):1710-9 - PubMed

Publication types

LinkOut - more resources