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. 2014 Jun 8;4(2):49-60.
eCollection 2014 Jun.

Modeling time resolved light propagation inside a realistic human head model

Sh Bazrafkan  1 , K Kazemi  1
Affiliations

Modeling time resolved light propagation inside a realistic human head model

Sh Bazrafkan et al. J Biomed Phys Eng. .

Abstract

Background: Near infrared spectroscopy imaging is one of the new techniques used for investigating structural and functionality of different body tissues. This is done by injecting light into the medium and measuring the photon intensity at the surface of the tissue.

Methods: In this paper the different medical applications, various imaging and simulation techniques of NIRS imaging is described. Each method is introduced and discussed. Then, the optimized model is prepared for numerical simulations. In this paper, the finite element method is used for solving the diffusion equation numerically.

Results: Diffusion equation was solved for realistic human head model using finite element approach for a point light source and time resolved case. The photon intensity distribution in different head layers has been shown and the intensity orientation via the CSF layer has been illustrated.

Conclusion: Simulating the photon transformation inside the tissue is essential for investigating the NIRS imaging technique. The finite element approach is a fast and accurate method for simulating this fact. The time resolved approach of this technique could illustrate the photon migration and intensity orientation in the tissue for time dependent light sources in tissues.

Keywords: Finite element method; Light propagation; Near infrared spectroscopy; Time resolved radiative transfer equation.

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Figures

Figure 1
Figure 1
Different molar extinction coefficient for oxy and de-oxy hemoglobin in near infrared wavelengths lead to different attenuation for each media [1].
Figure 2
Figure 2
Geometry of the applied model
Figure 3
Figure 3
Simulation of light propagation in the brain using FEM
Figure 4
Figure 4
Propagation distribution at time 1.2ns where light is crossing the scalp and is entering the CSF and brain
See this image and copyright information in PMC

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