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. 1989 Oct;63(10):4422-5.
doi: 10.1128/JVI.63.10.4422-4425.1989.

Trans activation by the bovine papillomavirus E2 protein in Saccharomyces cerevisiae

L C Morrissey  1 , J Barsoum, E J Androphy
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Trans activation by the bovine papillomavirus E2 protein in Saccharomyces cerevisiae

L C Morrissey et al. J Virol. 1989 Oct.

Abstract

The papillomavirus E2 protein functions as an enhancer-binding factor to promote transcription in mammalian cells. We found that one copy of the E2 binding site acted as an E2 protein-dependent upstream activating sequence in Saccharomyces cerevisiae. Additional copies of the binding motif further augmented transcription. These results imply that the E2 protein functionally interacts with highly conserved transcriptional elements.

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References

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