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. 2015 Jan 16;80(2):1275-8.
doi: 10.1021/jo502630t.

Copper-catalyzed synthesis of substituted quinolines via C–N coupling/condensation from ortho-acylanilines and alkenyl iodides

Lingkai Kong, Yuanyuan Zhou, He Huang, Yang Yang, Yuanyuan Liu, Yanzhong Li

Copper-catalyzed synthesis of substituted quinolines via C–N coupling/condensation from ortho-acylanilines and alkenyl iodides

Lingkai Kong et al. J Org Chem. .

Abstract

An efficient cascade copper-catalyzed intermolecular Ullmann-type C–N coupling/enamine condensation reaction is described, in which ortho-acylanilines and alkenyl iodides converted to multisubstituted quinolines in good to excellent yields.

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