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. 2015 Feb;10(2):233-7.
doi: 10.1002/cmdc.201402416. Epub 2014 Dec 15.

Investigating the anti-leishmanial effects of linear peptoids

Gabriela A Eggimann  1 , Hannah L Bolt, Paul W Denny, Steven L Cobb
Affiliations

Investigating the anti-leishmanial effects of linear peptoids

Gabriela A Eggimann et al. ChemMedChem. 2015 Feb.

Abstract

Peptoids, a class of peptide mimetics, have emerged as promising anti-infective agents against a range of bacterial infections. Herein we present the first study of the antiparasitic and specifically the anti-leishmanial properties of linear peptoids. Peptoids were identified as having promising activity against Leishmania mexicana axenic amastigotes, a causative agent of cutaneous leishmaniasis.

Keywords: Leishmania; anti-leishmanial agents; antiparasitic agents; peptoids.

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