Rebuttal from Stuart M. Phillips and Chris McGlory

Affiliations

¹ Department of Kinesiology, McMaster University, Hamilton, ON, Canada phillis@mcmaster.ca.
² Department of Kinesiology, McMaster University, Hamilton, ON, Canada.

Comment

Stuart M Phillips et al. J Physiol. 2014.

. 2014 Dec 15;592(24):5349.

doi: 10.1113/jphysiol.2014.284406.

¹ Department of Kinesiology, McMaster University, Hamilton, ON, Canada phillis@mcmaster.ca.
² Department of Kinesiology, McMaster University, Hamilton, ON, Canada.

No abstract available

Comment on

CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis.
Reid MB, Judge AR, Bodine SC. Reid MB, et al. J Physiol. 2014 Dec 15;592(24):5345-7. doi: 10.1113/jphysiol.2014.279406. J Physiol. 2014. PMID: 25512436 Free PMC article. No abstract available.

1. Bodine SC, Baehr LM. Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1. Am J Physiol Endocrinol Metab. 2014;307:E469–E484. - PMC - PubMed
1. Cunningham ML. A mouse is not a rat is not a human: species differences exist. Toxicol Sci. 2002;70:157–158. - PubMed
1. Reid MB, Judge AR, Bodine SC. CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis. J Physiol. 2014;592:5345–5347. - PMC - PubMed
1. Tesch PA, von Walden F, Gustafsson T, Linnehan RM, Trappe TA. Skeletal muscle proteolysis in response to short-term unloading in humans. J Appl Physiol (1985) 2008;105:902–906. - PMC - PubMed
1. Wall BT, Dirks ML, van Loon LJ. Skeletal muscle atrophy during short-term disuse: implications for age-related sarcopenia. Ageing Res Rev. 2013;12:898–906. - PubMed