Fertility: the role of mTOR signaling and KIT ligand
- PMID: 25517366
- DOI: 10.1016/j.cub.2014.09.033
Fertility: the role of mTOR signaling and KIT ligand
Abstract
Activation of a limited pool of diminishing ovarian follicles determines women's reproductive lifespan. A recent rodent study describes the role of mTOR signaling and KIT ligand in granulosa cells of primordial follicles for follicle activation and for reproductive lifespan regulation.
Copyright © 2014 Elsevier Ltd. All rights reserved.
Comment on
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Somatic cells initiate primordial follicle activation and govern the development of dormant oocytes in mice.Curr Biol. 2014 Nov 3;24(21):2501-8. doi: 10.1016/j.cub.2014.09.023. Epub 2014 Oct 23. Curr Biol. 2014. PMID: 25438940
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