Human somatic cell reprogramming: does the egg know best?
- PMID: 25517458
- DOI: 10.1016/j.stem.2014.10.011
Human somatic cell reprogramming: does the egg know best?
Abstract
Somatic cell nuclear transfer offers an alternative approach to the use of exogenous transcription factors for the reprogramming of somatic cells. But is it a better way? Two groups have performed detailed molecular comparisons between human cell lines made by the two methods and report different conclusions.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Comparable frequencies of coding mutations and loss of imprinting in human pluripotent cells derived by nuclear transfer and defined factors.Cell Stem Cell. 2014 Nov 6;15(5):634-42. doi: 10.1016/j.stem.2014.10.002. Epub 2014 Nov 6. Cell Stem Cell. 2014. PMID: 25517467
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