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Comment
. 2014 Nov 6;15(5):533-4.
doi: 10.1016/j.stem.2014.10.007. Epub 2014 Nov 6.

Pluripotent-stem-cell-derived epicardial cells: a step toward artificial cardiac tissue

Christoph Brenner  1 , Wolfgang-Michael Franz  2
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Pluripotent-stem-cell-derived epicardial cells: a step toward artificial cardiac tissue

Christoph Brenner et al. Cell Stem Cell. .
Free article

Abstract

Epicardial cells are crucial for heart development, function, and regeneration, but methods to study them have been lacking. Using WNT and BMP signaling pathways, Witty et al. (2014) have now developed an elaborate method to generate fully functional epicardial cells from human pluripotent stem cells, allowing their in vitro investigation.

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