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. 2014 Nov 6;15(5):535-6.
doi: 10.1016/j.stem.2014.10.012. Epub 2014 Nov 6.

Stem cells to insulin secreting cells: two steps forward and now a time to pause?

Jake A Kushner  1 , Patrick E MacDonald  2 , Mark A Atkinson  3
Affiliations
Free article

Stem cells to insulin secreting cells: two steps forward and now a time to pause?

Jake A Kushner et al. Cell Stem Cell. .
Free article

Abstract

Two groups recently reported the in vitro differentiation of human embryonic stem cells into insulin-secreting cells, achieving an elusive goal for regenerative medicine. Herein we provide a perspective regarding these developments, compare phenotypes of the insulin-containing cells to human β cells, and discuss implications for type 1 diabetes research and clinical care.

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