Hypertension: an immune disorder?
- PMID: 25517606
- DOI: 10.1016/j.immuni.2014.11.007
Hypertension: an immune disorder?
Abstract
T cell depletion can prevent hypertension in experimental animals. What is the nature of T cell activation in hypertension? In this issue of Immunity, Carnevale et al. (2014) implicate PlGF signaling in a reservoir of splenic T cells.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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The angiogenic factor PlGF mediates a neuroimmune interaction in the spleen to allow the onset of hypertension.Immunity. 2014 Nov 20;41(5):737-52. doi: 10.1016/j.immuni.2014.11.002. Epub 2014 Nov 7. Immunity. 2014. PMID: 25517614
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