Comment
doi: 10.1016/j.immuni.2014.11.004.
Epub 2014 Nov 20.
Tumors STING adaptive antitumor immunity
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- PMID: 25517609
- DOI: 10.1016/j.immuni.2014.11.004
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Comment
Tumors STING adaptive antitumor immunity
Immunity.
.
Free article
Abstract
Immunotherapy is revolutionizing the treatment of cancer patients, but the molecular basis for tumor immunogenicity is unclear. In this issue of Immunity, Deng et al. (2014) and Woo et al. (2014) provide evidence suggesting that dendritic cells detect DNA from tumor cells via the STING-mediated, cytosolic DNA sensing pathway.
Copyright © 2014 Elsevier Inc. All rights reserved.
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