Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Oct;30(10):1781-91.
doi: 10.1007/s00467-014-3030-1. Epub 2014 Dec 18.

Primary hyperoxalurias: diagnosis and treatment

Efrat Ben-Shalom  1 , Yaacov Frishberg
Affiliations
Review

Primary hyperoxalurias: diagnosis and treatment

Efrat Ben-Shalom et al. Pediatr Nephrol. 2015 Oct.

Abstract

Primary hyperoxalurias (PH) comprise a group of three distinct metabolic diseases caused by derangement of glyoxylate metabolism in the liver. Recent years have seen advances in several aspects of PH research. This paper reviews current knowledge of the genetic and biochemical basis of PH, the specific epidemiology and clinical presentation of each type, and therapeutic approaches in different disease stages. Potential future specific therapies are discussed.

PubMed Disclaimer

References

    1. N Engl J Med. 1968 Feb 1;278(5):233-8 - PubMed
    1. Pediatrics. 1952 Dec;10(6):660-6 - PubMed
    1. Nephrol Dial Transplant. 2012 Oct;27(10):3855-62 - PubMed
    1. J Pediatr. 2000 Feb;136(2):255-7 - PubMed
    1. Pediatr Transplant. 2000 Aug;4(3):177-81 - PubMed

MeSH terms

LinkOut - more resources