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. 2014 Feb 18;2(1):13.
doi: 10.1186/2052-0492-2-13. eCollection 2014.

A case of purpura fulminans caused by Hemophilus influenzae complicated by reversible cardiomyopathy

Akira Endo  1 , Atsushi Shiraishi  1 , Junichi Aiboshi  1 , Yoshiro Hayashi  2 , Yasuhiro Otomo  1
Affiliations

A case of purpura fulminans caused by Hemophilus influenzae complicated by reversible cardiomyopathy

Akira Endo et al. J Intensive Care. .

Abstract

Here, we report a case of a 41-year-old male diagnosed as septic shock with purpura fulminans (PF) infection. The causative organism was β-lactamase-negative ampicillin-resistant Hemophilus influenzae. He developed fulminant cardiac dysfunction approximately 1 h after admission, and the cause was considered to be septic cardiomyopathy. Blood pressure and oxygenation were maintained at adequate levels with the aid of extracorporeal membrane oxygenation (ECMO). The cardiac dysfunction was reversible, and he was successfully weaned from ECMO on day 12 of hospitalization. However, he needed amputation for all extremities because the infection spread to his limbs and eventually, succumbed to sepsis caused by empyema on day 34 of hospitalization. To the best of our knowledge, this is only the second case of PF caused by H. influenzae in an adult to be reported worldwide.

Keywords: Amputation; Disseminated intravascular coagulation; Symmetric peripheral gangrene.

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Figures

Figure 1
Figure 1
Images of the patient was taken on the day 1 (A, B) and on the day 9 (C) of hospitalization. Gangrene of the bilateral limbs, the facial region, and penis progressed gradually, and all limbs complicated with infection on the day 9.
See this image and copyright information in PMC

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