Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Dec;8(4):135-48.

The influence of pregnancy and lactation on maternal bone health: a systematic review

Pooneh Salari  1 , Mohammad Abdollahi  2
Affiliations

The influence of pregnancy and lactation on maternal bone health: a systematic review

Pooneh Salari et al. J Family Reprod Health. 2014 Dec.

Abstract

Osteoporosis is considered as an important public health problem especially in postmenopausal women. There are some hypotheses support the contributory effect of pregnancy and lactation on osteoporosis later in life. High calcium demand during pregnancy and lactation and low estrogenic state support those hypotheses. Numerous studies have investigated on the issue but there is no consensus about the contributory effect of pregnancy and lactation on osteoporosis. To explore the current state of fact, in the present study, all bibliographic databases were searched and all relevant studies on the topic of osteoporosis, lactation, and pregnancy were reviewed. The review shows that despite of controversial results, pregnancy may have protective effect on bone especially if followed by lactation.

Keywords: bone loss; lactation; parity; pregnancy.

PubMed Disclaimer

References

    1. Abdollahi M, Larijani B, Rahimi R, Salari P. Role of oxidative stress in osteoporosis. Therapy. 2005;2:787–96.
    1. Salari P, Abdollahi M. Controversial effects of non-steroidal anti-inflammatory drugs on bone: a review. Inflamm Allergy Drug Targets. 2009;8:169–75. - PubMed
    1. Salari P, Abdollahi M. A comprehensive review of the shared roles of inflammatory cytokines in osteoporosis and cardiovascular diseases as two common old people problem; action toward development of new drugs. Int J Pharmacol. 2011;7:552–67.
    1. Salari P, Larijani B, Abdollahi M. Association of hyperhomocysteinemia with osteoporosis: a systematic review. Therapy. 2008;5:215–22.
    1. Salari P, Rezaie A, Larijani B, Abdollahi M. A systematic review of the impact of n-3 fatty acids in bone health and osteoporosis. Med Sci Monit. 2008;14:RA37–RA44. - PubMed

LinkOut - more resources