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Review
. 1989 Nov 23;977(2):123-41.
doi: 10.1016/s0005-2728(89)80063-5.

Slip and leak in mitochondrial oxidative phosphorylation

M P Murphy  1
Affiliations
Review

Slip and leak in mitochondrial oxidative phosphorylation

M P Murphy. Biochim Biophys Acta. .

Abstract

During oxidative phosphorylation by mammalian mitochondria part of the free energy stored in reduced substrates is dissipated and energy is released as heat. Here I review the mechanisms and the physiological significance of this phenomenon.

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