Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Dec 22;6(12):6020-47.
doi: 10.3390/nu6126020.

Resources and biological activities of natural polyphenols

An-Na Li  1 , Sha Li  2 , Yu-Jie Zhang  3 , Xiang-Rong Xu  4 , Yu-Ming Chen  5 , Hua-Bin Li  6
Affiliations
Review

Resources and biological activities of natural polyphenols

An-Na Li et al. Nutrients. .

Abstract

The oxidative stress imposed by reactive oxygen species (ROS) plays an important role in many chronic and degenerative diseases. As an important category of phytochemicals, phenolic compounds universally exist in plants, and have been considered to have high antioxidant ability and free radical scavenging capacity, with the mechanism of inhibiting the enzymes responsible for ROS production and reducing highly oxidized ROS. Therefore, phenolic compounds have attracted increasing attention as potential agents for preventing and treating many oxidative stress-related diseases, such as cardiovascular diseases, cancer, ageing, diabetes mellitus and neurodegenerative diseases. This review summarizes current knowledge of natural polyphenols, including resource, bioactivities, bioavailability and potential toxicity.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Different groups of polyphenols and their chemical structures.
Figure 2
Figure 2
Some bioactivities of natural polyphenols.
See this image and copyright information in PMC

References

    1. Pandey K.B., Rizvi S.I. Plant polyphenols as dietary antioxidants in human health and disease. Oxidative Med. Cell. Longev. 2009;2:270–278. doi: 10.4161/oxim.2.5.9498. - DOI - PMC - PubMed
    1. Arts I.C., Hollman P.C. Polyphenols and disease risk in epidemiologic studies. Am. J. Clin. Nutr. 2005;81:317–325. - PubMed
    1. Kondratyuk T.P., Pezzuto J.M.J.P. Natural product polyphenols of relevance to human health. Pharm. Biol. 2004;42:46–63. doi: 10.3109/13880200490893519. - DOI
    1. Spencer J.P., Abd E.M.M., Minihane A.M., Mathers J.C. Biomarkers of the intake of dietary polyphenols: Strengths, limitations and application in nutrition research. Br. J. Nutr. 2008;99:12–22. - PubMed
    1. Kuhnau J. The flavonoids. A class of semi-essential food components: Their role in human nutrition. World Rev. Nutr. Diet. 1976;24:91–117. - PubMed

Publication types

MeSH terms