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. 1989 Oct;103(2):371-6.
doi: 10.1017/s0950268800030715.

Investigation of an outbreak of hepatitis A simplified by salivary antibody testing

A R Bull  1 , K J Kimmance, J V Parry, K R Perry
Affiliations

Investigation of an outbreak of hepatitis A simplified by salivary antibody testing

A R Bull et al. Epidemiol Infect. 1989 Oct.

Abstract

In March 1988 a general practitioner notified two cases of hepatitis A in a private boarding school. Epidemiological investigation, including testing for salivary antibodies revealed a further five cases and established immunity to, and recent infection with, hepatitis A virus (HAV). The pattern of the outbreak was described. A number of practices which would encourage cross-infection were corrected. Normal human immunoglobulin was given to contacts. Repeat salivary testing 10 weeks later revealed that two more boys had become reactive for anti-HAV, though at a low titre. These may have been serological responses to HAV infection modified by the passive immunization.

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