Microvascular endothelial cells poised to take center stage in experimental renal fibrosis
- PMID: 25535302
- PMCID: PMC4378115
- DOI: 10.1681/ASN.2014121170
Microvascular endothelial cells poised to take center stage in experimental renal fibrosis
Keywords: TGF-β; hypoxia; tubulointerstitial.
Comment on
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Curtailing endothelial TGF-β signaling is sufficient to reduce endothelial-mesenchymal transition and fibrosis in CKD.J Am Soc Nephrol. 2015 Apr;26(4):817-29. doi: 10.1681/ASN.2013101137. Epub 2014 Dec 22. J Am Soc Nephrol. 2015. PMID: 25535303 Free PMC article.
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- Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH: Transforming growth factor type beta: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci U S A 83: 4167–4171, 1986 - PMC - PubMed
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- Böttinger EP: TGF-beta in renal injury and disease. Semin Nephrol 27: 309–320, 2007 - PubMed
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