Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Sep;58(5):616-21.
doi: 10.4103/0019-5049.144669.

Blood transfusion practices in cardiac anaesthesia

Affiliations
Review

Blood transfusion practices in cardiac anaesthesia

Hanumantha Rao Mangu et al. Indian J Anaesth. 2014 Sep.

Abstract

The primary reasons for blood transfusion in cardiac surgery are to correct anaemia and to improve tissue oxygen delivery. However, there is a considerable debate regarding the actual transfusion trigger at which the benefits of transfusion overweight the risk. The association between extreme haemodilution, transfusion and adverse outcome after cardio pulmonary bypass (CPB) is not clear and the current available literature is not sufficient to provide a strong recommendation regarding the safe haematocrit range during CPB. There is no quality evidence to support use of fresh red blood cell except during massive transfusion or exchange transfusion in neonate. Overall concern regarding the safety of allogeneic blood transfusion resulted in the search for autologous blood transfusion and perioperative blood salvage. The aim of this review is to provide cardiac surgery specific clinically useful guidelines pertaining to transfusion triggers, optimal haemodilution during CPB, autologous blood transfusion and role of perioperative blood salvage based on available evidence.

Keywords: Blood transfusion; cardiac surgery; cardiopulmonary bypass.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared

References

    1. Shaw RE, Johnson CK, Ferrari G, Brizzio ME, Sayles K, Rioux N, et al. Blood transfusion in cardiac surgery does increase the risk of 5-year mortality: Results from a contemporary series of 1714 propensity-matched patients. Transfusion. 2014;54:1106–13. - PubMed
    1. Bhaskar B, Dulhunty J, Mullany DV, Fraser JF. Impact of blood product transfusion on short and long-term survival after cardiac surgery: More evidence. Ann Thorac Surg. 2012;94:460–7. - PubMed
    1. Ranganathan P, Ahmed S, Kulkarni AP, Divatia JV. Appropriateness of perioperative blood transfusion in patients undergoing cancer surgery: A prospective single-centre study. Indian J Anaesth. 2012;56:234–7. - PMC - PubMed
    1. Gomathi G, Varghese RG. Audit of use of blood and its components in a tertiary care center in South India. Asian J Transfus Sci. 2012;6:189. - PMC - PubMed
    1. Practice Guidelines for blood component therapy: A report by the American society of anesthesiologists task force on blood component therapy. Anesthesiology. 1996;84:732–47. - PubMed