[Osteoimmunnology and periodontitis]
- PMID: 25536794
[Osteoimmunnology and periodontitis]
Abstract
Periodontal disease is a pathological condition that involves inflammation of the tooth supporting structures. Accumulated lines of evidence suggest that hyperimmune responses to periodontal bacteria result in the destruction of periodontal connective tissue and alveolar bone. In this review, we discuss several aspects of the immune-inflammatory host response that ultimately results in loss of alveolar bone and stimulates osteoclastogenesis.