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Review
. 2014 Oct;41(5):357-63.
doi: 10.1159/000366176. Epub 2014 Sep 15.

The Rhesus Site

Franz F Wagner  1 , Willy A Flegel  1
Affiliations
Review

The Rhesus Site

Franz F Wagner et al. Transfus Med Hemother. 2014 Oct.

Abstract

The Rhesus Site is a resource for information of the 'Rhesus' blood group. It is intended for specialists and non-specialists. The website details research in the field relevant for transfusion medicine, immunohematology, and molecular research. Link areas guide to important publications and to methodological resources for Rhesus. Many data originally presented at The Rhesus Site have been formally published later. The 'RhesusBase' section represents the largest database for RHD alleles; the 'RhesusSurveillance' section details the results of the largest prospective observational study on anti-D immunization events in D-positive patients. Visitors to the website are encouraged to explore the intricacies of the most complex blood group gene locus.

Keywords: Antigen D; Databases as topic; Immunization; Rh blood group; Rh-Hr blood group system.

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Figures

Fig. 1
Fig. 1
The graphic appearance of The Rhesus Site, when visitors access its URL (www.uni-ulm.de/wflegel/RH/). Beneath the heading and a horizontal bar, the first section has links to 4 major areas of scientific research in the Rh blood group system.
Fig. 2
Fig. 2
Methods section of The Rhesus Site. The links lead to detailed descriptions of major methods in the RH field. Features include video clips depicting RBC freezing and a protocol to determine the D antigen densities, which was used during an international workshop.
Fig. 3
Fig. 3
View of the RhesusBase. In the left frame (‘Gene shown’), a grouping criterion can be selected. In this example, ‘D category’ was chosen. In the right frame showing a table (‘D category’), all related RHD alleles are listed, which link to files detailing the information known for any given allele. The original RhesusBase (version 1) has been replaced by the current version RhesusBase V2, which is hosted by the University of Ulm webserver.
Fig. 4
Fig. 4
Rhesus Immunization Registry (RIR) – results page. The contributing serologist, type and titer of anti-D, possible immunization risk, and RHD allele involved are listed. For example, the 2 original samples of DNB were entries 2 and 3 [25].
See this image and copyright information in PMC

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