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Multicenter Study
. 2014 Dec 25:14:362.
doi: 10.1186/s12888-014-0362-0.

The prediction of treatment outcomes by early maladaptive schemas and schema modes in obsessive-compulsive disorder

Nicola Thiel  1 , Brunna Tuschen-Caffier  2 , Nirmal Herbst  3 , Anne Katrin Külz  4 , Christoph Nissen  5 , Elisabeth Hertenstein  6 , Ellen Gross  7 , Ulrich Voderholzer  8
Affiliations
Multicenter Study

The prediction of treatment outcomes by early maladaptive schemas and schema modes in obsessive-compulsive disorder

Nicola Thiel et al. BMC Psychiatry. .

Abstract

Background: Higher levels of early maladaptive schemas (EMS) and schema modes according to schematherapy by Jeffrey Young are present in obsessive-compulsive disorder (OCD) compared to healthy controls. This study examines the relationship of EMS and schema modes to OC symptom severity and the predictive value of EMS and schema modes on treatment outcome in inpatients receiving Cognitive-Behavioral Therapy (CBT) with Exposure and Response Prevention (ERP). The main assumption was a negative association between the EMS of the domain 'disconnection' and dysfunctional coping and parent schema modes and the treatment outcome.

Methods: EMS, schema modes, depression and traumatic childhood experiences were measured in 70 patients with OCD. To analyze the predictors, two regression analyses were conducted considering multiple variables, such as depression, as covariates.

Results: Regression analyses demonstrated that higher scores on the EMS named failure and emotional inhibition and depressive symptom severity at pretreatment were significantly related to poor outcome and explained a high percentage of the variance in OC symptoms at posttreatment. No influence on the treatment outcome was observed for schema modes, other EMS or other covariates.

Conclusions: The results support the approach to extend the CBT with ERP treatment with therapeutic elements focusing on maladaptive schemas, particularly in non-responders.

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