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Case Reports
. 2014 Nov;5(Suppl 1):S71-4.
doi: 10.4103/0976-3147.145211.

Extensive heterotopic ossification in patient with tubercular meningitis

Vijai Prakash Sharma  1 , Ganesh Yadav  1 , Anil Kumar Gupta  1 , Dileep Kumar  1
Affiliations
Case Reports

Extensive heterotopic ossification in patient with tubercular meningitis

Vijai Prakash Sharma et al. J Neurosci Rural Pract. 2014 Nov.

Abstract

Tubercular meningitis is a severe form of central nervous system tuberculosis with high morbidity and mortality. Apart from neurological deficits, musculoskeletal involvement is also seen in very few cases in the form of heterotopic ossification around immobile joints. A 35-year-old male case of tubercular meningitis with left hemiparesis presented with multiple joint restriction of range of motion. On clinical examination, palpable firm masses around multiple joints with painful restriction of movements were seen. X-ray films of multiple joints revealed heterotopic ossification over left shoulder, hip and knee joint with bony ankylosis of left hip and soft tissue contractures. Very few reports have been published in the literature for association of heterotopic ossification with tubercular meningitis with such extensive joint involvement which compels us to report this clinical association of tubercular meningitis. This report is intended to create caution among physicians and other caregivers for this debilitating complication of tubercular meningitis and in face of high prevalence of tuberculosis and tubercular meningitis, employ methods to prevent and treat.

Keywords: Heterotopic ossification; heterotopic ossification in hemiparesis; neurogenic heterotopic ossification; rehabilitation in heterotopic ossification; tubercular meningitis.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
(a) Patient with TBM and left-sided hemiparesis, (b) Left hand deformity, (c) Left hip and knee deformity with ankle equinus
Figure 2
Figure 2
X-ray of patient showing extensive heterotopic ossification around left hip with ankylosis of left hip
Figure 3
Figure 3
X-ray of left knee showing heterotopic ossification around knee joint: (a) AP view (b) Lateral view
Figure 4
Figure 4
X-ray of the left shoulder in PA view in adducted (a) and abducted (b) Position showing heterotopic ossification, With left abduction orthosis with left dynamic cock-up splint (c)
See this image and copyright information in PMC

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