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. 2014 Dec 10:5:704.
doi: 10.3389/fmicb.2014.00704. eCollection 2014.

Far from being well understood: multiple protein phosphorylation events control cell differentiation in Bacillus subtilis at different levels

Jan Gerwig  1 , Jörg Stülke  1
Affiliations

Far from being well understood: multiple protein phosphorylation events control cell differentiation in Bacillus subtilis at different levels

Jan Gerwig et al. Front Microbiol. .
No abstract available

Keywords: EpsB; PtkA; biofilm formation; cross-talk; tyrosine phosphorylation.

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Figures

Figure 1
Figure 1
Schematic overview how the bacterial tyrosine kinases PtkA and EpsB control cell differentiation at different levels. The PtkA kinase controls sporulation and biofilm matrix expression by acting upstream of the central regulator of cell differentiation Spo0A by an unknown mechanism. In contrast, the EpsB kinase acts downstream of the Spo0A protein and controls exopolysaccharide production by phosphorylation of the glycosyltransferase EpsE. Arrows indicate activating effects, T-bars inhibitory effects. EPS, extracellular polysaccharides; P, phosphate group.
See this image and copyright information in PMC

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