Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2015 Feb 1:147:76-80.
doi: 10.1016/j.drugalcdep.2014.12.003. Epub 2014 Dec 15.

Mediators of a smoking cessation intervention for persons living with HIV/AIDS

Damon J Vidrine  1 , George Kypriotakis  2 , Liang Li  3 , Roberto C Arduino  4 , Faith E Fletcher  5 , Irene Tamí-Maury  2 , Ellen R Gritz  2
Affiliations
Randomized Controlled Trial

Mediators of a smoking cessation intervention for persons living with HIV/AIDS

Damon J Vidrine et al. Drug Alcohol Depend. .

Abstract

Background: Cigarette smoking among persons living with HIV (PLWH) is a pressing public health concern, and efforts to evaluate cessation treatments are needed. The purpose of the present study was to assess potential mechanisms of a cell phone-delivered intervention for HIV-positive smokers.

Methods: Data from 350 PLWH enrolled in a randomized smoking cessation treatment trial were utilized. Participants were randomized to either usual care (UC) or a cell phone intervention (CPI) group. The independent variable of interest was treatment group membership, while the dependent variable of interest was smoking abstinence at a 3-month follow-up. The hypothesized treatment mechanisms were depression, anxiety, social support, quit motivation and self-efficacy change scores.

Results: Abstinence rates in the UC and CPI groups were 4.7% (8 of 172) and 15.7% (28 of 178), respectively. The CPI group (vs. UC) experienced a larger decline in depression between baseline and the 3-month follow-up, and a decline in anxiety. Self-efficacy increased for the CPI group and declined for the UC group. Quit motivation and social support change scores did not differ by treatment group. Only self-efficacy met the predefined criteria for mediation. The effect of the cell phone intervention on smoking abstinence through change in self-efficacy was statistically significant (p<0.001) and accounted for 17% of the total effect of the intervention on abstinence.

Conclusions: The findings further emphasize the important mechanistic function of self-efficacy in promoting smoking cessation for PLWH. Additional efforts are required to disentangle the relationships between emotional, distress motivation, and efficacious smoking cessation treatment.

Keywords: Cell phone intervention; HIV/AIDS; Mediation; Smoking cessation; This trial has been registered at clinicaltrials.gov [NCT00502827]..

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest:

The authors have no conflict of interest to disclose.

Figures

Figure 1
Figure 1
Mediation results of intervention on smoking abstinence with change scores of self-efficacy from baseline to 3 months. **=p < 0.01; ***=p < 0.001.
See this image and copyright information in PMC

References

    1. Allison PD. Change scores as dependent variables in regression analysis. In: Clogg, Clogg CC, editors. Sociological Methodology Basil. Blackwell; Oxford: 1990. pp. 93–114.
    1. AMA. Health care needs of gay men and lesbians in the United States. Council on Scientific Affairs, American Medical Association. JAMA. 1996;275:1354–1359. - PubMed
    1. Breslau N, Johnson EO. Predicting smoking cessation and major depression in nicotine-dependent smokers. Am J Public Health. 2000;90:1122–1127. - PMC - PubMed
    1. Browning KK, Wewers ME, Ferketich AK, Diaz P. Tobacco use and cessation in HIV-infected individuals. Clin Chest Med. 2013;34:181–190. - PMC - PubMed
    1. Burke M, Furman A, Hoffman M, Marmor S, Blum A, Yust I. Lung cancer in patients with HIV infection: is it AIDS-related? HIV Med. 2004;5:110–114. - PubMed

Publication types