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. 1989 Aug 31;75(4):345-50.
doi: 10.1177/030089168907500409.

Is the Epstein-Barr virus involved in Hodgkin's disease?

M Boiocchi  1 , A Carbone, V De Re, R Dolcetti
Affiliations

Is the Epstein-Barr virus involved in Hodgkin's disease?

M Boiocchi et al. Tumori. .

Abstract

EBV genomes, in clonal episomal form, were detected in 7 out of 17 cases of Hodgkin's disease (HD) and in a single case of non-Hodgkin's lymphoma which occurred in a patient after therapeutic treatment for HD. The experimental data presented imply that a clonal cell population, harboring the EBV genome, must be present in EBV-positive HD. In light of this finding we are attempting to reconsider the abundant literature on this lymphoproliferative disorder, and suggest a reevaluation of the possibility that EBV could be etiologically involved in HD.

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