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Case Reports
. 2015 Mar-Apr;28(2):79-82.
doi: 10.1111/dth.12188. Epub 2014 Dec 29.

Ingenol mebutate gel treatment for actinic cheilitis: report of four cases

Nerea Barrado Solís  1 , Paula Molés Poveda, César Lloret Ruiz, Virginia Pont Sanjuan, Manel Velasco Pastor, Esther Quecedo Estébanez, Javier Miquel Miquel
Affiliations
Case Reports

Ingenol mebutate gel treatment for actinic cheilitis: report of four cases

Nerea Barrado Solís et al. Dermatol Ther. 2015 Mar-Apr.

Abstract

Actinic cheilitis (AC) are premalignant lesions that have an increased risk of malignant transformation. Their treatment, therefore, is essential to prevent carcinogenesis. However, optimal therapy is not well established and different modalities yield variable results. Ingenol mebutate gel has recently been approved by the US Food and Drug Administration for topical treatment of actinic keratosis, with high clearance rates. On the basis of these findings, we report our experience with this drug for the treatment of AC.

Keywords: actinic cheilitis; field-directed therapy; ingenol mebutate gel.

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