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. 2014 Dec 27;6(12):241-7.
doi: 10.4240/wjgs.v6.i12.241.

Systematic review of absorbable vs non-absorbable sutures used for the closure of surgical incisions

Muhammad S Sajid  1 , Malcolm R McFall  1 , Pauline A Whitehouse  1 , Parv S Sains  1
Affiliations

Systematic review of absorbable vs non-absorbable sutures used for the closure of surgical incisions

Muhammad S Sajid et al. World J Gastrointest Surg. .

Abstract

Aim: To report a systematic review of published randomized controlled trials (RCTs) investigating the role of absorbable suture (AS) against non-AS (NAS) used for the closure of surgical incisions.

Methods: RCTs investigating the use of AS vs NAS for the closure of surgical incisions were statistically analysed based upon the principles of meta-analysis and the summated outcomes were represented as OR.

Results: The systematic search of medical literature yielded 10 RCTs on 1354 patients. Prevalence of wound infection (OR = 0.97; 95%CI: 0.56, 1.69; Z = 0.11; P = 0.92) and operative morbidity (P = 0.45) was comparable in both groups. Nonetheless, the use of AS lead to lower risk of wound break-down (OR = 0.12; 95%CI: 0.04, 0.39; Z = 3.52; P < 0.0004).

Conclusion: This meta-analysis of 10 RCTs demonstrates that the use of AS is similar to NAS for skin closure for surgical site infection and other operative morbidities. AS do not increase the risk of skin wound dehiscence, rather lead to a reduced risk of wound dehiscence compared to NAS.

Keywords: Absorbable sutures; Non-absorbable suture; Skin closure; Surgical site infection; Wound dehiscence.

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Figures

Figure 1
Figure 1
PRISMA flow chart showing trial selection methodology. RCT: Randomized controlled trial.
Figure 2
Figure 2
Strength and summary of the evidence analysed on GradePro®.
Figure 3
Figure 3
Forest plot for surgical site infection following the use of absorbable suture and non-absorbable suture for skin closure. Odds ratios are shown with 95%CI. AS: Absorbable stitch; NAS: Non-absorbable stitch.
Figure 4
Figure 4
Forest plot for postoperative complications following the use of absorbable suture and non-absorbable suture for skin closure. Odds ratios are shown with 95%CI. AS: Absorbable stitch; NAS: Non-absorbable stitch.
Figure 5
Figure 5
Forest plot for the risk of wound dehiscence following the use of absorbable suture and non-absorbable suture for skin closure. Odds ratios are shown with 95%CI. AS: Absorbable stitch; NAS: Non-absorbable stitch.
See this image and copyright information in PMC

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