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. 2014:2014:956856.
doi: 10.1155/2014/956856. Epub 2014 Dec 4.

Giant malignant phyllodes tumour of breast

Ramakrishnan Krishnamoorthy  1 , Thejas Savasere  1 , Vinod Kumar Prabhuswamy  1 , Rajashekhara Babu  1 , Sadashivaiah Shivaswamy  1
Affiliations

Giant malignant phyllodes tumour of breast

Ramakrishnan Krishnamoorthy et al. Case Rep Oncol Med. 2014.

Abstract

The term phyllodes tumour includes lesions ranging from completely benign tumours to malignant sarcomas. Clinically phyllodes tumours are smooth, rounded, and usually painless multinodular lesions indistinguishable from fibroadenomas. Percentage of phyllodes tumour classified as malignant ranges from 23% to 50%. We report a case of second largest phyllodes tumour in a 35-year-old lady who presented with swelling of right breast since 6 months, initially small in size, that progressed gradually to present size. Examination revealed mass in the right breast measuring 36×32 cms with lobulated firm surface and weighing 10 kgs. Fine needle aspiration cytology was reported as borderline phyllodes; however core biopsy examination showed biphasic neoplasm with malignant stromal component. Simple mastectomy was done and specimen was sent for histopathological examination which confirmed the core biopsy report. Postoperatively the patient received chemotherapy and radiotherapy. The patient is on follow-up for a year and has not shown any evidence of metastasis or recurrence.

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Figures

Figure 1
Figure 1
Anterior view of the tumour.
Figure 2
Figure 2
Lateral view of the tumour.
Figure 3
Figure 3
Intraoperative picture showing separation of the tumour from chest wall.
Figure 4
Figure 4
Chest wall after excision.
Figure 5
Figure 5
Postoperative picture.
Figure 6
Figure 6
Gross specimen.
Figure 7
Figure 7
Cut surface of the specimen.
Figure 8
Figure 8
Histopathological picture showing high mitotic index with epithelial and high stromal proliferation.
See this image and copyright information in PMC

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