Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014:2014:641015.
doi: 10.1155/2014/641015. Epub 2014 Dec 8.

Oral verruciform xanthoma: a case report and literature review

Yonara Maria Freire Soares Marques  1 , Cleverton Roberto de Andrade  2 , Suzana Cantanhede Orsini Machado de Sousa  3 , Cláudia Maria Navarro  4
Affiliations

Oral verruciform xanthoma: a case report and literature review

Yonara Maria Freire Soares Marques et al. Case Rep Pathol. 2014.

Abstract

Oral verruciform xanthoma represents an uncommon entity, which affects mainly oral mucosa. This paper presents the major clinical and histological features of oral verruciform xanthoma and reports a case on the tongue. The differential diagnosis and a literature review are also provided in light of recent information.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Clinical consistency of OVX with granular, yellow-whitish surface in the lateral border of the tongue (a); photomicrograph of OVX (H and E; 100x) showing the connective tissue exhibiting the accumulation of foam cell between the epithelial rete pegs (b); low magnification 10x of the lesion exhibiting the uniform rete pegs with parakeratotic invaginating crypts and connective tissue filled with xanthoma cells (c); negative image of fat and PAS-positive granules inside the cytoplasm (high magnification 400x) (d); and strong positive immunoreactivity to antibody CD-68 (high magnification 200x) (e).
See this image and copyright information in PMC

References

    1. Philipsen H. P., Reichart P. A., Takata T., Ogawa I. Verruciform xanthoma—biological profile of 282 oral lesions based on a literature survey with nine new cases from Japan. Oral Oncology. 2003;39(4):325–336. doi: 10.1016/S1368-8375(02)00088-X. - DOI - PubMed
    1. Oliveira P. T., Jaeger R. G., Cabral L. A. G., Carvalho Y. R., Costa A. L. L., Jaeger M. M. M. Verruciform xanthoma of the oral mucosa. Report of four cases and a review of the literature. Oral Oncology. 2001;37(3):326–331. doi: 10.1016/S1368-8375(00)00068-3. - DOI - PubMed
    1. Poulopoulos A. K., Epivatianos A., Zaraboukas T., Antoniades D. Verruciform xanthoma coexisting with oral discoid lupus erythematosus. British Journal of Oral and Maxillofacial Surgery. 2007;45(2):159–160. doi: 10.1016/j.bjoms.2005.06.020. - DOI - PubMed
    1. Kakarantza-Angelopoulou E., Nicolatou O., Anagnostopoulou S. Verruciform xanthoma of the palate: case report with electron microscopy. Journal of Oral and Maxillofacial Surgery. 1991;49(4):409–412. doi: 10.1016/0278-2391(91)90381-U. - DOI - PubMed
    1. Santa Cruz D. J., Martin S. A. Verruciform xanthoma of the vulva: report of two cases. American Journal of Clinical Pathology. 1979;71(2):224–228. - PubMed

LinkOut - more resources