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Case Reports
. 2015 Mar;53(3):1031-3.
doi: 10.1128/JCM.03623-14. Epub 2014 Dec 31.

Four carbapenem-resistant gram-negative species carrying distinct carbapenemases in a single patient

Baixing Ding  1 , Fupin Hu  1 , Yang Yang  1 , Qinglan Guo  1 , Jinwei Huang  1 , Minggui Wang  2
Affiliations
Case Reports

Four carbapenem-resistant gram-negative species carrying distinct carbapenemases in a single patient

Baixing Ding et al. J Clin Microbiol. 2015 Mar.

Abstract

Carbapenem-resistant Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii were isolated from a single patient, each producing different carbapenemases (NDM-1, KPC-2, IMP, and OXA-23, respectively). The NDM-1-producing E. coli strain was preceded by a clonally related carbapenem-susceptible strain a month earlier, suggesting in vivo acquisition of blaNDM-1.

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Figures

FIG 1
FIG 1
The timeline of bacterial isolation and antibiotic use. All the preservation isolates were identified from sputum samples, except an E. coli isolate from the urine on 11 October and a K. pneumoniae isolate from the CSF sample on 12 October.
See this image and copyright information in PMC

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