Metastatic renal cell carcinoma to the testis: A case report and review of the literature

Abstract

This is a case of a 68-year-old male who presented with a chief compliant of a testicular mass, which was discovered to be a meta-static lesion of undiagnosed renal cell carcinoma. A computed tomography scan revealed a large right renal mass and multiple pulmonary metastasis. Shortly after diagnosis, the patient was initiated on systemic therapy and received a cytoreductive nephrectomy. We discuss the details of this case as well as a pertinent review of metastatic renal cell carcinoma to the testes.

Fig. 1

Left testicular mass measuring 3.5 × 2.5 × 2.3 cm.

Fig. 2

Right renal mass, heterogenous measuring 12.2 × 8.1 cm.

Fig. 3

Right renal mass.

Fig. 4a

Pulmonary metastasis prior to cytoreductive nephrectomy.

Fig. 4b

Pulmonary metastasis prior to cytoreductive nephrectomy.

Fig. 5

Pulmonary metastasis 3 months after cytoreductive nephrectomy.

Fig. 6

Gross photograph showing well-circumscribed yellow and hemorrhagic mass confined to the testicle.

Fig. 7a

Renal cell carcinoma, clear cell type showing small nested and alveolar growth pattern with higher grade nuclear morphology on the right (hematoxylin and eosin 100×).

Fig. 7b

Renal cell carcinoma showing strong membranous staining with CD10 (CD10 immunostain; 100×).

Fig. 7c

Renal cell carcinoma showing a negative result with cytokeratin 7 stain (CK7 immunostain; 100×).