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Case Reports
. 2015 Jan;35(1):159-61.
doi: 10.3343/alm.2015.35.1.159. Epub 2014 Dec 8.

Two cases of acute lymphoblastic leukemia with an e1a3 BCR-ABL1 fusion transcript

Affiliations
Case Reports

Two cases of acute lymphoblastic leukemia with an e1a3 BCR-ABL1 fusion transcript

Sang-Yong Shin et al. Ann Lab Med. 2015 Jan.

Erratum in

No abstract available

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Conflict of interest statement

No potential conflicts of interest relevant to this article were reported.

Figures

Fig. 1
Fig. 1
Multiplex reverse transcriptase (RT)-PCR with sequencing analysis and BCR-ABL1 gene mutation study for imatinib resistance. Multiplex RT-PCR and sequencing analysis revealed the e1a3 BCR-ABL1 fusion transcript in patient 1 (A, B) and patient 2 (C, D). BCR-ABL1 gene mutation study was performed for imatinib resistance in patient 2 (E, F). The mutation was detected 12 months after treatment. The 736th nucleotide (empty arrow) of the ABL1 gene was changed from G to A [NM_005157.4: c.763G>A (p.Glu255Lys)].

References

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