Evaluation of inbreeding and genetic variability of five pig breeds in czech republic

Abstract

The complex analysis of the pedigree records of Czech Landrace (CLA), Czech Large White-dam line (CLWd), Czech Large White-sire line (CLWs), Duroc (DC), and Pietrain (PN) was performed to determine trends of genetic diversity (GD), and to find the main sources of the GD loss. The total size of the pedigree was 132,365, 391,151, 32,913, 13,299, and 7,160 animals in CLA, CLWd, CLWs, DC, and PN, respectively. Animals born in the years 2011 through 2013 were assumed as the reference population. The average pedigree completeness index for one generation back was 95.9%, 97.4%, 91.2%, 89.8%, and 94.2% for appropriate breeds. Number of ancestors explaining 100% of gene pool was 186, 373, 125, 157, and 37 in CLA, CLWd, CLWs, DC, and PN, respectively. The relative proportion of inbred animals (58%, 58%, 54%, 47%, and 25%), the average inbreeding (2.7%, 1.4%, 2.5%, 3.6%, and 1.3%) and the average co-ancestry (3.1%, 1.6%, 3.3%, 4.2%, and 3.3%) were found over the past decade in analysed breeds. The expected inbreeding under random mating increased during the last 10 years in CLWs and PN and varied from 1.27% to 3.2%. The effective population size computed on the basis of inbreeding was 76, 74, 50, 35, and 83 in 2012 in CLA, CLWd, CLWs, DC, and PN, respectively. The shortest generation interval (1.45) was observed for CLWd in sire to son selection pathway. The longest generation interval obtained PN (1.95) in sire to daughter pathway. The average relative GD loss within last generation interval was 7.05%, 4.70%, 9.81%, 7.47%, and 10.46%, respectively. The relative proportion of GD loss due to genetic drift on total GD loss was 85.04%, 84.51%, 89.46%, 86.19%, and 83.68% in CLA, CLWd, CLWs, DC, and PN, respectively. All breeds were characterized by a high proportion of inbred animals, but the average inbreeding was low. The most vulnerable breeds to loss of GD are DC and PN. Therefore, a breeding program should be more oriented to prevent the increase of GD loss in these breeds.

Keywords: Effective Population Size; Expected Inbreeding; Genetic Diversity Loss; Number of Founders; Pedigree Analysis; Pedigree Completeness; Pig.

Figure 1

i) Pedigree completeness index in (a) Czech Landrace (CLA), (b) Czech Large White dam line (CLWd) (c) Czech Large White sire line (CLWs), (d) Duroc (DC, and (e) Pietrain (PN) breed.

Figure 2

Proportion of inbreeding in evaluated breeds. CLA, Czech Landrace; CLWd, Czech Large White dam line; CLWs, Czech Large White sire line; DC, Duroc; PN, Pietrain,

Figure 3

Cumulative marginal contribution of 100 ansectors in evaluated breeds. CLA, Czech Landrace; CLWd, Czech Large White dam line; CLWs, Czech Large White sire line; DC, Duroc; PN, Pietrain.

Figure 4

The genetic diversity loss due to (a) unequal founder contribution and random genetic drift (1 − GD), (b) random genetic drift (GD−GD*), and (c) unequal founder contribution (1−GD*) in evaluated breeds. CLA, Czech Landrace; CLWd, Czech Large White dam line; CLWs, Czech Large White sire line; DC, Duroc; PN, Pietrain.