An overview on the correlation of neurological disorders with cardiovascular disease

Abstract

Neurological disorders (NDs) are one of the leading causes of death especially in the developed countries. Among those NDs, Alzheimer's disease (AD) and Parkinson disease (PD) are heading the table. There have been several reports in the scientific literatures which suggest the linkage between cardiovascular disorders (CVDs) and NDs. In the present communication, we have tried to compile NDs (AD and PD) association with CVDs reported in the literature. Based on the available scientific literature, we believe that further comprehensive study needs to be done to elucidate the molecular linking points associated with the above mentioned disorders.

Keywords: AD, Alzheimer’s disease; APP, amyloid precursor protein; Alzheimer’s disease; Aβ; Aβ, β amyloid; CVD, cardiovascular disease; Cardiovascular disease; DA, dopamine; Dopamine; LBs, Lewy bodies; Neurological disorders; PD, Parkinson disease; Parkinson disease; l-DOPA, l-dihydroxyphenylalanine; α-Synuclein.