Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Dec;9(4):627-31.
doi: 10.5114/wiitm.2014.45734. Epub 2014 Oct 7.

The DIAMOND system in the treatment of type 2 diabetes mellitus in an obese patient

Affiliations
Case Reports

The DIAMOND system in the treatment of type 2 diabetes mellitus in an obese patient

Jarosław Kozakowski et al. Wideochir Inne Tech Maloinwazyjne. 2014 Dec.

Abstract

Obesity and type 2 diabetes mellitus have reached epidemic proportions worldwide. As the majority of antidiabetic medications are of limited efficacy and patient adherence to long-term therapy is one of the main limiting factors of effective blood glucose and body weight control, new therapies are still looked for. The DIAMOND system seems to be one of the most promising among them. This system recognizes natural electrical activity of the stomach and automatically applies electrical stimulation treatment during/after eating with subsequent modulation of signals transmitted to the regulatory centers in the brain in order to provoke an early response of the gut typical of a full meal. We present the case of a 47-year-old obese woman with type 2 diabetes. During treatment with this system, serum glucose and hemoglobin A1c levels significantly decreased. Body weight loss and waist circumference reduction were observed. Additionally, beneficial effect on lipid profile was found.

Keywords: diabetes mellitus; gastric electrical stimulation; obesity.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Placement of the leads implanted in the wall of the stomach (permission from MetaCure Ltd)
Photo 1
Photo 1
Rechargeable implantable pulse generator (IPG) (permission from MetaCure Ltd)
Figure 2
Figure 2
Scheme of the study protocol

Similar articles

References

    1. World Health Organization. Global strategy on diet, physical activity and health. 2008. Available at: http://www.who.diet.int/dietphysicalactivity/publications/facts/obesity/en.
    1. World Health Organization. World Health Organization: diabetes facts sheet. 2011. http://www.who.int/mediacentre/factsheets/fs312/en/index.html.
    1. Koro CE, Bowlin SJ, Bourgeois N, Fedder DO. Glycemic control from 1998 to 2000 among U.S. adults diagnosed with type 2 diabetes: a preliminary report. Diabetes Care. 2007;27:17–20. - PubMed
    1. Morton GJ, Cummings DE, Baskin DG, Schwartz MW. Central nervous system control of food intake and body weight. Nature. 2006;443:289–95. - PubMed
    1. Cummings DE, Overduin J. Gastrointestinal regulation of food intake. J Clin Invest. 2007;117:13–23. - PMC - PubMed

Publication types

LinkOut - more resources