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Comparative Study
. 1989 Dec;27(12):2858-60.
doi: 10.1128/jcm.27.12.2858-2860.1989.

Comparison of monoclonal antibodies for rapid detection of cytomegalovirus in spin-amplified plate cultures

R Ashley  1 , E Peterson, H Abbo, D Gold, L Corey
Affiliations
Comparative Study

Comparison of monoclonal antibodies for rapid detection of cytomegalovirus in spin-amplified plate cultures

R Ashley et al. J Clin Microbiol. 1989 Dec.

Abstract

Cytomegalovirus (CMV) was detected in 56 of 275 specimens (20%); 50 of 56 (89%) were detected by conventional culture, and 37 (66%) were detected by rapid assay at 72 h with a commercial monoclonal antibody and a pooled monoclonal antibody. Although the two antibodies were equally sensitive at 72 h, the pooled antibody gave a brighter, more easily detected signal. Other viruses were isolated from 9 specimens (3.3%) by conventional culture. Use of rapid assays alone fails to detect slow-growing CMV and non-CMV viral pathogens.

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References

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