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. 2015 Jan;22(1):5-7.
doi: 10.1038/nsmb.2942.

Discovery and annotation of long noncoding RNAs

John S Mattick  1 , John L Rinn  2
Affiliations

Discovery and annotation of long noncoding RNAs

John S Mattick et al. Nat Struct Mol Biol. 2015 Jan.

Abstract

Recent advances in RNA-sequencing technologies have led to the discovery of thousands of previously unannotated noncoding transcripts, including many long noncoding RNAs (lncRNAs) whose functions remain largely unknown. Here we discuss considerations and best practices in lncRNA identification and annotation, which we hope will foster functional and mechanistic exploration.

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References

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