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. 2015 Jan;56(1):73-80.

Total cystectomy and subsequent urinary diversion to the prepuce or vagina in dogs with transitional cell carcinoma of the trigone area: a report of 10 cases (2005-2011)

Kohei Saeki  1 , Atsushi Fujita  1 , Naoki Fujita  1 , Takayuki Nakagawa  1 , Ryohei Nishimura  1
Affiliations

Total cystectomy and subsequent urinary diversion to the prepuce or vagina in dogs with transitional cell carcinoma of the trigone area: a report of 10 cases (2005-2011)

Kohei Saeki et al. Can Vet J. 2015 Jan.

Abstract
in English, French

The cases of 10 dogs with transitional cell carcinoma of the urinary bladder that underwent total cystectomy were retrospectively reviewed to evaluate the feasibility and outcome of total cystectomy and ureteral transplantation to the prepuce or vagina. Dehiscence of ureterostomy (n = 2), pyelonephritis (n = 3), oliguria (n = 2), azotemia (n = 1), and ureteral obstruction (n = 1) were observed complications. The estimated median survival time was 385 days. This study demonstrates the feasibility of total cystectomy and subsequent urinary diversion to the prepuce or vagina in dogs. Compared to previous ureterocolonic anastomosis, this technique is associated with fewer gastrointestinal and neurologic complications.

Cystectomie totale et diversion urinaire subséquente au prépuce ou au vagin de chiens atteints du carcinome transitionnel de la région du trigone vésical : rapport sur 10 cas (2005–2011). Les cas de 10 chiens atteints du carcinome transitionnel de la vessie urinaire qui avaient subi une cystectomie totale ont été examinés rétrospectivement afin d’évaluer la faisabilité et les résultats d’une cystectomie totale et d’une transplantation urétérale au prépuce ou au vagin. La déhiscence de l’urétérostomie (n = 2), la pyélonéphrite (n = 3), l’oligurie (n = 2), l’azotémie (n = 1) et une obstruction urétérale (n = 1) figuraient parmi les complications observées. L’estimation de la durée médiane de survie était de 385 jours. Cette étude démontre la faisabilité d’une cystectomie totale et d’une diversion urinaire subséquente vers le prépuce ou le vagin chez les chiens. Comparativement à l’anastomose urétérocolique antérieure, cette technique est associée à moins de complications gastro-intestinales et neurologiques.(Traduit par Isabelle Vallières).

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Figures

Figure 1
Figure 1
Representative images during and after total cystectomy and ureteral transplantation. A — Isolation of the urinary bladder and urethra in a female dog. B — Isolation of the penis and distal urethra with a peritoneal approach in a male dog. C — After removal of the penis and distal urethra, hemostatic forceps was inserted into the abdominal cavity through the opening at the preputial mucosa made by a small trepan, and abdominal wall. The distal tip of the resected ureter was grasped by the forceps and, as the forceps was withdrawn, it was led to outside of the body through the opening. D — Final appearance of the Prepuce technique. The ureter was sutured to the novel orifice. In this case, 1 ureter was transplanted after nephrectomy of the dysfunctional kidney. E, F — In female dogs, novel opening of the ureter was made at the vagina using a small trepan. In this case, the ureter was anastomosed to the vagina with end-to-side anastomosis. G — Final appearance of the Vagina A technique. In this dog, 1 ureter was anastomosed to another (end-to-side anastomosis) and then connected to the vagina with 1 orifice (end-to-end anastomosis) since the ureter was sufficiently dilated to enable end-to-end anastomosis, instead of end-to-side anastomosis, to the vagina. H — Final appearance of the Vagina B procedure. Both ureters were transplanted into the vagina with 2 separate orifices (end-to-side anastomosis). White arrowhead — urethra; black arrowhead — ureter; black arrow — novel opening at the prepuce; * — vagina.
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References

    1. Knapp DW, McMillan SK. Tumors of the urinary system. In: Withrow SJ, Vail DM, Page R, editors. Withrow and MacEwen’s Small Animal Clinical Oncology. 5th ed. Philadelphia, Pennsylvania: WB Saunders; 2012. pp. 572–582.
    1. Mutsaers AJ, Widmer WR, Knapp DW. Canine transitional cell carcinoma. J Vet Intern Med. 2003;17:136–144. - PubMed
    1. Knapp DW, Glickman NW, DeNicola DB, Bonney PL, Lin TL, Glickman LT. Naturally-occurring canine transitional cell carcinoma of the urinary bladder: A relevant model of human invasive bladder cancer. Urol Oncol. 2000;5:47–59. - PubMed
    1. Morgan TM, Kaffenberger SD, Cookson MS. Surgical and chemotherapeutic management of regional lymph nodes in bladder cancer. J Urol. 2012;188:1081–1088. - PubMed
    1. Norris AM, Laing EJ, Valli VE, et al. Canine bladder and urethral tumors: A retrospective study of 115 cases (1980–1985) J Vet Intern Med. 1992;6:145–153. - PubMed

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