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Case Reports
. 2014 Nov 26;6(3):274-8.
doi: 10.1159/000369992. eCollection 2014 Sep.

The 'pantie' tumour

Affiliations
Case Reports

The 'pantie' tumour

Silada Kanokrungsee et al. Case Rep Dermatol. .

Abstract

We present a case of radiation-associated angiosarcoma. A 67-year-old Thai woman was diagnosed with endometrium carcinoma stage IC and was treated with surgery and radiations. Ten years later, she presented with a gradually enlarging mass on the pubic area, in the shape of a pair of panties. Skin biopsy of lesions confirmed angiosarcoma. The diagnosis was radiation-associated angiosarcoma. She was treated with chemotherapy due to unresectable tumour. The chemotherapy was started with paclitaxel 70 mg/m(2) every 2 weeks. After completing the fifth cycle of paclitaxel, the lesion was markedly decreased in size and the symptoms previously described were also completely resolved.

Keywords: Angiosarcoma; Radiation; Sarcoma; Vascular tumour.

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Figures

Fig. 1
Fig. 1
A large indurated violaceous plaque on the suprapubic area.
Fig. 2
Fig. 2
a Poorly circumscribed dermal tumours extending to the subcutaneous tissue. Haematoxylin and eosin, original magnification ×40. b Atypical cells with little mitosis, some forming irregular dissecting anastomosing lumen. Haematoxylin and eosin, original magnification ×600.

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References

    1. Coindre JM, Terrier P, Guillou L, Le Doussal V, Collin F, Ranchere D, Sastre X, Vilain MO, Bonichon F, N'Guyen Bui B. Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas: a study of 1240 patients from the French Federation of Cancer Centers Sarcoma Group. Cancer. 2001;91:1914–1926. - PubMed
    1. Fayette J, Martin E, Piperno-Neumann S, Le Cesne A, Robert C, Bonvalot S, Ranchère D, Pouillart P, Coindre JM, Blay JY. Angiosarcomas, a heterogeneous group of sarcomas with specific behavior depending on primary site: a retrospective study of 161 cases. Ann Oncol. 2007;18:2030–2036. - PubMed
    1. Arlen M, Higinbotham NL, Huvos AG, Marcove RC, Miller T, Shah IC. Radiation-induced sarcoma of bone. Cancer. 1971;28:1087–1099. - PubMed
    1. Brenn T, Fletcher CD. Radiation-associated cutaneous atypical vascular lesions and angiosarcoma: clinicopathologic analysis of 42 cases. Am J Surg Pathol. 2005;29:983–996. - PubMed
    1. Lucas DR. Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesion. Arch Pathol Lab Med. 2009;133:1804–1809. - PubMed

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