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Case Reports
. 2014 Sep-Dec;37(3):449-53.
doi: 10.4321/s1137-66272014000300017.

[Clindamycin as adjuvant therapy in Staphilococcal skin scalded syndrome]

[Article in Spanish]
F J Gil Sáenz  1 , M Herranz Aguirre, G Durán Urdániz, L Zandueta Pascual, J Gimeno Ballester, E Bernaola Iturbe
Affiliations
Free article
Case Reports

[Clindamycin as adjuvant therapy in Staphilococcal skin scalded syndrome]

[Article in Spanish]
F J Gil Sáenz et al. An Sist Sanit Navar. 2014 Sep-Dec.
Free article

Abstract

Staphylococcal scalded skin syndrome (SSSS) is a dermatologic disease caused by exotoxins produced by Staphylococcus aureus. The disease presents as a painful cutaneous rash that culminates with the detachment of the superficial dermis. The usual treatment is antibiotics with beta-lactamase resistant penicillin. We report the case of a patient who presented with SSSS with initial torpid evolution despite antibiotic treatment and after the introduction of clindamycin IV experienced a very significant improvement. Concerns about the increase of methicillin resistant Staphylococcus aureus (MRSA) and the pathophysiology of this disease make bacteriostatic spectrum antistaphylococcal antibiotics, such as clindamycin, strong candidates for consideration as a first-line therapeutic arsenal for the treatment of SSSS.

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