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Case Reports
. 2015 Jan 7:2015:bcr2014205688.
doi: 10.1136/bcr-2014-205688.

Borrelial pseudolymphoma of the nose

Affiliations
Case Reports

Borrelial pseudolymphoma of the nose

Mosab Tariq Mohanna et al. BMJ Case Rep. .

Abstract

A 52-year-old Colombian woman, a patient with psoriasis, undergoing phototherapy with (ultraviolet B narrowband) UVBnb, presented with a symptomless solitary diffuse erythaematous plaque on her nose for 3 months. Initially, she was treated with pimecrolimus 1% cream for 8 weeks, which was then combined with metronidazole cream for 4 weeks, with the initial diagnosis of UV-triggered rosacea, without improvement. A punch biopsy was performed and the histology showed a pseudolymphomatous reaction. The diagnosis of nasal pseudolymphoma of borreliosis was confirmed with PCR. The lesion completely resolved following oral doxycycline therapy.

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Figures

Figure 1
Figure 1
Diffuse erythaematous plaque on the center of the nose.
Figure 2
Figure 2
Pseudolymphomatous reaction of lymphocytes, histiocytes and plasma cells within the dermis (H&E stain).
Figure 3
Figure 3
Sixty per cent of lymphocytes in the infiltrate express T-cell markers (CD3 stain).
Figure 4
Figure 4
Forty per cent of lymphocytes in the infiltrate express B-cell markers (CD20 stain).

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