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. 2014 Aug;68(4):239-43.
doi: 10.5455/medarh.2014.68.239-243. Epub 2014 Jul 31.

Bacterial uropathogens isolates and antibiograms in children under 5 years of age

Mohamed Alkhatim Alsammani  1 , Mohamed Issa Ahmed  1 , Nahla Farouk Abdelatif  1
Affiliations

Bacterial uropathogens isolates and antibiograms in children under 5 years of age

Mohamed Alkhatim Alsammani et al. Med Arch. 2014 Aug.

Abstract

Background: Childhood urinary infections are among the most common febrile illnesses occurring during this period with varying susceptibility to antibiotic.

Aim: The aim of this study was to identify uropathogens responsible to for urinarytract infection (UTIs) in children less than 5 years of age, and determine the antibiograms of the isolates to commonly used antibiotics.

Patients and methods: Hundred and four children (2 months - 5 years old) seen at the Gadarif Teaching Hospital from January 2012 and December 2013 were evaluated. A urine specimen was obtained by a plastic bag with an adhesive backing around an opening or by direct voiding into sterile container. Urine was examined microscopically and those with significant pyuria and bacteruria were further cultured and microorganisms were identified and tested for antimicrobial susceptibility.

Results: Out of 304 children suffering from UTIs; 145(47.7%) had significant pyuria of them; 54(17.8 %) had positive bacterial growth. The frequency of sex and residency were almost the same. E. coli (42.6%) was the most common uropathogen, sensitive to ciprofloxacin (91.3%), followed by Pseudomonas aeruginosa (29.6%) sensitive to Ciprofloxacin (75%)and Norofloxacin (68.8%), Klebsiellapneumoniae (18.5%) sensitive to Ciprofloxacin and Norofloxacin and Nalidixic acid (90%) and Proteus mirabilis sensitive to Ciprofloxacin and Norofloxacin (90%), Amoxicillin / clavulanic acid (Augmentin(80%).

Conclusion: The most common uropathogens were E. coli, Pseudomonas aeruginosa,Klebsiellapneumoniae, and Proteus mirabilis. Ciprofloxacin is the recommended initial empirical therapy while awaiting the culture and sensitivity results.

Keywords: antimicrobial; pediatrics; resistance; sensitivity; urinary tract infection.

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Conflict of interest statement

CONFLICT OF INTEREST: NONE DECLARED.

Figures

Figure 1
Figure 1
Types of bacterial isolates
Figure 2
Figure 2
Distribution of uropathogens in males according to age group
Figure 3
Figure 3
Distribution of uropathogens in females according to age group
See this image and copyright information in PMC

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