On the brink: a new synaptic vesicle release model at the calyx of held
- PMID: 25569343
- DOI: 10.1016/j.neuron.2014.12.038
On the brink: a new synaptic vesicle release model at the calyx of held
Abstract
How vesicle calcium sensors interact with calcium channels at synapses affects neurotransmitter release dynamics. In this issue of Neuron, Nakamura et al. (2015) propose that synaptic vesicles are tightly coupled around the perimeter of a voltage-gated calcium channel cluster.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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Nanoscale distribution of presynaptic Ca(2+) channels and its impact on vesicular release during development.Neuron. 2015 Jan 7;85(1):145-158. doi: 10.1016/j.neuron.2014.11.019. Epub 2014 Dec 18. Neuron. 2015. PMID: 25533484 Free PMC article.
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