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Comment
. 2015 Jan 7;85(1):6-8.
doi: 10.1016/j.neuron.2014.12.038.

On the brink: a new synaptic vesicle release model at the calyx of held

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On the brink: a new synaptic vesicle release model at the calyx of held

Melissa A Herman et al. Neuron. .
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Abstract

How vesicle calcium sensors interact with calcium channels at synapses affects neurotransmitter release dynamics. In this issue of Neuron, Nakamura et al. (2015) propose that synaptic vesicles are tightly coupled around the perimeter of a voltage-gated calcium channel cluster.

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